"Health wise I am feeling great. I am a big supporter of trials - it allows new treatments and drugs to be brought in.”
A trial looking at monitoring early prostate cancer to decide whether or not treatment is needed
This trial is looking at assessing men with early prostate cancer to see if their cancer grows before they decide whether or not to have treatment.
Doctors usually treat early prostate cancer with surgery or radiotherapy. But treatment for prostate cancer can have many side effects and sometimes prostate cancer can be very slow growing. So doctors may choose an approach called active surveillance before deciding whether or not to give treatment. This means that, before they give treatment, doctors will keep a close eye on (observe) the cancer to see if it grows.
The researchers in this trial want to find out what happens to the cancer when they observe instead of giving treatment straight away. They aim to find out
- How many men will need treatment in the future because their cancer continues to grow
- How many men will never need treatment because the cancer doesn’t grow
The men taking part will give blood and urine samples, and have MRI scans of their prostate. The doctors in this trial will use these to try and predict if the cancer will grow. The results of this trial may help doctors to improve treatment for prostate cancer in the future.
Please note - if you took part in this trial before July 2013 you will have had repeat biopsies as well as MRI scans.
Who can enter
The researchers will store some of the blood samples in a blood bank and they may be used for future research.
You will also have an MRI scan of your prostate every 2 years.
If the results of any of your tests show that your cancer is starting to grow, the doctor will then discuss treatment options with you.
Before you can enter the trial, the doctor will examine you and you will have some tests, including blood tests. You will also have to have an MRI scan of your lower tummy area (abdomen).
You will need to go to the hospital to see the doctor and to have your blood tests. You will also go to the hospital at least every 2 years to have an MRI scan of your prostate.
There are no treatments in this trial. You may get a small bruise where your blood sample is taken.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr C. Parker
Institute of Cancer Research (ICR)
NIHR Clinical Research Network: Cancer
The Royal Marsden NHS Foundation Trust