A trial looking at a new way for family doctors to check moles to see if they need to be seen by a specialist (The MoleMate UK Trial)

Cancer type:

Skin cancer





This trial looked at a new type of scanner to see if it could help family doctors (GPs) decide more easily which moles may be melanoma skin cancer.

If you are worried about a mole on your body, you should have it checked by your GP. Your GP may decide that you should see a skin specialist (dermatologist). But it can be very difficult for GPs to decide who may have a melanoma. If they referred everyone who came to see them to a specialist immediately, the system would get jammed and those needing urgent appointments wouldn't be able to get them.

This trial looked at a system called MoleMate. Researchers thought it may help GPs to spot melanoma more easily. If this was so, some people might not need to see a dermatologist unnecessarily. But, if it shows your GP that you do need an urgent referral, it could mean that you start treatment for melanoma sooner.

The MoleMate system is a hand held scanner, linked to a computer. It scans features in moles and takes pictures. The computer asks the doctor questions about these pictures. It then advises whether or not you should see a dermatologist.

The aim of this trial was to see if the MoleMate system helped GPs to make more appropriate referrals for suspected melanoma.

Summary of results

The trial team found that the MoleMate system didn’t help GPs make more appropriate referrals to dermatologists.

The trial recruited 1,297 people. Some people had more than 1 mole so this made a total of 1,573 moles that were checked.

It was a randomised trial. Everybody who took part was put into 1 of 2 groups

  • 654 people with a total of 785 moles were checked in the standard way
  • 643 people with a total of 788 moles were checked using the MoleMate system

The researchers looked at the number of referrals that were appropriate. They considered a referral was appropriate if the dermatologist decided to take a tissue sample (biopsy) of the mole, or if it needed to be regularly checked. The number of appropriate referrals was about the same in both groups.

Both doctors and patients thought very positively about the MoleMate system. Overall this resulted in a higher number of referrals by doctors who used the system than those who used the standard way. But the trial team concluded that there was no evidence that using the MoleMate system improved the appropriateness of referrals for suspected melanomas.     

We have based this summary on information from the team who ran the trial. The information they sent us has been reviewed by independent specialists (peer reviewed Open a glossary item) and published in a medical journal. The figures we quote above were provided by the trial team. We have not analysed the data ourselves.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr Fiona Walter

Supported by

Addenbrookes Hospital
Biocompatibles UK Limited
MedX Health (holds trademark for MoleMate)
NHS Cambridgeshire
NIHR Clinical Research Network: Cancer
University of Cambridge

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:

Oracle 1422

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Charlie took part in a trial to try new treatments

A picture of Charlie

“I think it’s really important that people keep signing up to these type of trials to push research forward.”

Last reviewed:

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