Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
A study to learn more about the causes of mouth cancer
The researchers want to study cells from normal mouth tissue as well as from people who have mouth diseases, including mouth cancer. They will take samples from people who are having a biopsy, and from people who are having treatment for mouth cancer.
The aim of the study is to find out which gene changes are important, and how these changes may affect the way the immune system responds to cancer.
Please note – you will not benefit directly from taking part in this study. The results may help researchers understand more about what causes mouth cancer. And in the future may help them to improve treatment.
Who can enter
You can enter this trial if you are having a mouth biopsy or treatment for mouth cancer at Southampton University Hospitals NHS Trust, Poole Hospital NHS Foundation Trust or Portsmouth Hospitals NHS Trust.
If you are having a biopsy, the researchers will take some of the tissue that is removed. They may also take an extra biopsy of healthy mouth tissue.
If you are having surgery, the researchers will take a sample of the cancer that is removed.
If you are having
The study team will ask everybody taking part to give a blood sample when you have your biopsy or treatment, and again 3 months later.
If you agree to take part in this study, there will not be any additional hospital visits, apart from having an extra blood test after 3 months.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Gareth Thomas
Experimental Cancer Medicine Centre (ECMC)
NIHR Clinical Research Network: Cancer
University Hospital Southampton NHS Foundation Trust
University of Southampton