Last year in the UK over 60,000 cancer patients enrolled on clinical trials aimed at improving cancer treatments and making them available to all.
A study to find out more about the causes of some types of lymphoma and chronic leukaemia
This study is looking at blood, bone marrow, tissue and spit (saliva) samples from people with white blood cell (lymphocyte) disorders, to discover more about the causes and possible future treatments.
More about this trial
Conditions where lymphocytes have become cancerous are called lymphoproliferative disorders and include
- Chronic lymphocytic leukaemia (CLL)
- Mantle cell lymphoma
- Follicular lymphoma
- Hairy cell leukaemia
- Splenic lymphoma with villous lymphocytes
Doctors want to find out more about these cancerous cells. In this study you will give samples of blood and any extra
The aim of this study is to understand more about how changes to certain genes, proteins and sugars could affect how these diseases develop. This may help develop new treatments for these conditions in future.
You will not have any direct benefit from taking part in this study, and it is unlikely to change your treatment plan in any way. But the results of the study will be used to help people with cancer in the future.
Who can enter
Everyone taking part will have a study blood test at the time they are diagnosed, and when you come to the hospital for your follow up appointments, so the team can monitor changes in the blood cells. You will also give a sample of spit (saliva).
The team will ask permission to study any stored samples of bone marrow or lymphatic tissue that you have had removed as part of your routine treatment. They will also look at your medical notes to see how you are getting on.
You will have your study blood test and give your saliva sample when you are already at the hospital for your follow up appointments. So you will not need to make any extra visits to hospital.
As there are no treatments in this study, there are no side effects. You may have a small bruise where you had your blood tests.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr N K Potter
Cancer Research UK
Experimental Cancer Medicine Centre (ECMC)
Kay Kendall Leukaemia Fund
Tenovus Solentside Committee
University Hospital Southampton NHS Foundation Trust