Last year in the UK over 60,000 cancer patients enrolled on clinical trials aimed at improving cancer treatments and making them available to all.
A study using MRI scan to see how well chemotherapy is working in people with bowel cancer
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This study is looking at using a new type of MRI scan to see how well chemotherapy is working in people with bowel (colorectal) cancer.
The researchers think a new type of MRI scan, called a DW MRI scan, may work just as well at finding out about both of these.
The aim of this study is to find out how good the DW MRI scan is at finding out how well chemotherapy is working and if bowel cancer has spread.
Who can enter
You may be able to enter this trial if you go to a cancer clinic at the Imperial College Healthcare NHS Trust and you
- Have bowel cancer that has spread to another part of your body
- Have at least 1 area of cancer that measures 2cm or more and can be measured on a scan
- Are well enough to be up and about for at least half the day (performance status 0, 1 or 2)
- Are willing to use reliable contraception during the study if there is any chance you or your partner could become pregnant
- Are at least 18 years old
You cannot enter this trial if you
- Are taking any drug that affects blood vessel growth (your doctor can tell you about this)
- Have had chemotherapy or radiotherapy in the past month
- Have a large amount of fluid collected around your tummy (ascites)
- Have a pacemaker or other metal in your body
- Can’t stand to be in small spaces (you are claustrophobic)
- Are unable to lie flat and still for at least an hour
This study will recruit 25 people who go to a cancer clinic at the Imperial College Healthcare NHS Trust.
Everyone will have a MRI scan at the Charing Cross Hospital before starting chemotherapy. You have another scan within 2 weeks after your first chemotherapy treatment.
The researchers will ask some people to have a 2nd MRI scan before starting chemotherapy. You have this at the same visit as the 1st scan, with a short break in between.
You have 2 visits to Charing Cross Hospital as part of the trial. Each will last about an hour.
If you are having the 2nd scan, your first visit will be about 30 to 40 minutes longer.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Rohini Sharma
Engineering and Physical Sciences Research Council (EPSRC)
Imperial College London
Imperial College of Science Technology and Medicine
Medical Research Council (MRC)
NIHR Clinical Research Network: Cancer