A study looking at magnetic resonance imaging (MRI) scans to assess Hodgkin lymphoma in children and young people - MELT

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Blood cancers
Children's cancers
Hodgkin lymphoma





A study looking at using a new type of MRI scan to assess Hodgkin lymphoma and its response to treatment in children and young people.

The study is for children and young people up to and including the age of 20. We use the term 'you' in this summary, but if you are a parent, we are referring to your child.

Hodgkin lymphoma is a cancer of the lymphatic system.  It can start in many parts of the body including the lymph nodes, spleen, bone marrow, blood or other organs of the body.

Doctors will often use a CT scan, PET scan, MRI scan and ultrasound scan to find out where the Hodgkin lymphoma is.  They will also use these scans to find out how well it has responded after treatment. The researchers want to compare the new type of MRI scan to these scans.

The aim of this study is to find out how good the new type of MRI scan is at assessing Hodgkin lymphoma and its response to treatment.

Who can enter

You may be able to enter this trial if you

  • Have Hodgkin lymphoma
  • Are taking part in the Euronet PHL-C1 trial or LP1 trial OR are to have chemotherapy according to the Euronet trials – your doctor can advise about this
  • Are 5 to 20 years old

You cannot enter this trial if you

  • Are not able to have an MRI scan - if you have certain types of metal surgical clips or plates in your body, or a pacemaker for example
  • Have had cancer before unless there has been no sign of your disease in the past 5 years
  • Have had chemotherapy or radiotherapy in the past 2 years
  • Are pregnant or breastfeeding

Trial design

This study will recruit 55 children and young people who attend the University College London Hospital.

You will have the new type of MRI scan as well as the standard scans before and after your treatment.  The researchers will then compare these MRI scans with your standard scans to see which is better.

Hospital visits

There are no extra hospital visits if you take part in this trial.  But the new type of MRI scan will take about 1 hour to do each time.

Side effects

You may have a reaction to the injection for the scan.  This could include sweating, rash and difficulty breathing.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Stuart Taylor

Supported by

Cancer Research UK
NIHR Clinical Research Network: Cancer
University College London (UCL)

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:

Oracle 8635

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Over 60,000 cancer patients enrolled on clinical trials in the UK last year.

Last reviewed:

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