"I was delighted to take part in a clinical trial as it has the potential to really help others in the future.”
A study looking at improving quality of life for people with mesothelioma of the chest (RESPECT-Meso)
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This study is looking at ways to improve the quality of life of people with mesothelioma of the chest (pleural mesothelioma).
More about this trial
People living with mesothelioma of the chest (pleural mesothelioma) may have physical and psychological symptoms which can affect their
Researchers want to find out if giving specialist palliative care help early in mesothelioma treatment can improve quality of life and wellbeing for people throughout the course of their illness. They also want to find out how this may improve the wellbeing of family or friends closest to them.
Who can enter
You may be able to join this study if all of the following apply. You
- Have mesothelioma of the chest (pleural mesothelioma)
- Have been diagnosed within the past 6 weeks
- Are well enough to carry out all your normal activities, apart from heavy physical work (performance status of 0 or 1)
You cannot join this study if any of these apply
- You have had any other cancer in the last 5 years apart from carcinoma in situ of the cervix ,or squamous cell skin cancer that was successfully treated, or prostate cancer that hasn’t spread
- Your medical team needed to refer you to the specialist palliative care team when you were diagnosed or they have already referred you
- You are already taking part in another clinical trial that isn't looking at mesothelioma and that could affect your quality of life. If you have previously taken part in such a clinical trial it must be more than 3 months ago
- You agree to take part in another clinical trial for mesothelioma that could affect your quality of life within 3 months of being put into your group for this trial
- You are to have surgery to remove some or all of your mesothelioma (you may be able to take part if you had surgery to diagnose your condition or to relieve symptoms - your doctor can tell you this)
- You have already started chemotherapy for mesothelioma
- You have been in hospital for depression, anxiety or another mental condition in the past year
- You have any other medical condition that could affect you taking part in this trial
The researchers need about 174 people to join this study.
It is a randomised study. The people taking part are put into treatment groups by a computer. Neither you nor your doctor will be able to decide which group you are in. There are 2 groups in this trial.
People in group 1 will be referred to have early symptom control treatment and support from a palliative care specialist, as well as the usual treatment and support.
People in group 2 have the usual treatment and support.
The trial team will ask you to fill out some questionnaires at the start of the study, and then every month for 6 months. Some of these will be completed over the telephone. The questionnaire will ask about how you’ve been feeling and how the mesothelioma is affecting your life. This is called a quality of life study.
The researchers will ask your carer to take part in the study. They will fill out similar questionnaires to the ones you do. If your carer doesn’t want to take part they don’t have to. You can still take part in the study.
You go to the hospital to see the trial team once at the start of the study and again at 3 months and 6 months into the study.
You go to the hospital every month to see the Specialist Palliative Care Nurse, if you are in that group. As far as possible, they will make the appointments at the same time you are at the hospital for other appointments.
There are no side effects from taking part in this study.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Anoop Chauhan
British Lung Foundation
Health and Care Research Wales
H.A.S.A.G (Hampshire Asbestos Support and Awareness Group)
NIHR Clinical Research Network: Cancer
Oxford Respiratory Trials Unit
Portsmouth Hospitals NHS Trust