Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
A study looking at the immune system in people with and without cancer
This study is looking into how cells of the immune system in people with a solid tumour may differ from the immune systems of healthy people. A
We all suffer from many
The team would like to learn more about how different immune cells behave at different stages of the cancer journey. For example, how they are affected by treatment. They will ask people with and without cancer to give blood samples and in some cases tissue samples to see if they can find antibodies and immune cells that could fight cancer.
You will not get any direct benefit from taking part in this study, and it is unlikely to change any treatment plan in any way. But the results of the study will be used to help people with cancer in the future.
Who can enter
You may be able to enter this study if you are at least 18 years old and are in one of the following situations
- You have any solid cancer (any cancer apart from leukaemia or lymphoma)
- You are a friend or relative of someone having treatment for cancer at Southampton General Hospital, are of a similar age and are healthy
You cannot enter this study if you
- Have a low number of red blood cells (you have
anaemia) – your red blood cell count should be above 11g/dl – you can check this with your doctor
- Have had a
blood transfusionfrom a donor in the last 3 weeks
- Are very unwell
This study will look at samples from people with and without cancer.
Everyone taking part will give a series of blood samples for the team to study. If you have had surgery to remove your cancer (or are going to have surgery), the team will ask to look at some of the cancer tissue.
The number, timing and type of samples you give depend on whether or not you have cancer. And, if you have cancer, whether or not you are having treatment, and the type you are having. Before you join the study, the team will talk to you about how many hospital visits this would mean.
Where possible you will give your blood samples at the same time as you are having other routine blood tests. The team will tell you if you need to make any extra hospital visits for these.
As any tissue you give for the study will have already been removed, or will be removed as routine during your surgery, you will not have any side effects from this.
You may have a small bruise where you gave your blood sample.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Christian Ottensmeier
Experimental Cancer Medicine Centre (ECMC)
University Hospital Southampton NHS Foundation Trust
University of Southampton