"I now know how cancer can strike anyone whatever their situation or circumstance. I hope by taking part in a trial it will help others in my position in the future.”
A study looking at the genetic causes of testicular cancer (The Leeds Testicular Cancer Study)
This study is trying to find out more about the causes of testicular cancer and to identify genes that may be important in the development of this disease. This study is supported by Cancer Research UK.
The risk factors for testicular cancer include having a family history. We know from research that genetic factors may affect your risk of testicular cancer. But although family history is a known risk factor, it is rare for more than one person in a family to have testicular cancer.
In this study, the researchers will look at the
The aim of the study is to identify genes that could increase the risk of testicular cancer.
Who can enter
You may be able to enter this study if you
- Have or have had testicular cancer
- Are at least 18 years old
You can enter this study even if you are still having treatment for testicular cancer.
The researchers would like you to invite your parents to take part in this study. They would also like you to invite a male friend (not a relative) who hasn’t had testicular cancer. You can still take part if any or all of them don’t wish to take part.
This trial will recruit 1,000 men who have, or have had, testicular cancer. When you go to see your doctors for a follow up appointment, they may ask you if you would be interested in taking part in the study. Or you may get a letter from your hospital asking you to take part.
If you agree to take part, you will complete a questionnaire about your medical history and family history. Nobody in your family will be contacted without your permission.
You will need to give a small sample of blood. This may be at your GP surgery or hospital, depending on how your local services are arranged. The DNA from your blood sample will be safely stored and only used in this study. The researchers will look at the DNA to try and find genes that may increase the risk of developing testicular cancer.
The researchers will ask your permission to get a sample of tissue taken in your original operation for testicular cancer. This tissue sample will also only be used for the purpose of this study. They will also ask for permission to look at your medical records.
If your parents or friend choose to take part they will also complete a questionnaire and will be asked to give a blood sample.
Taking part in this study does not involve any extra visits to your hospital, apart from having the blood test.
You may have some bruising in the area where the blood sample is taken. There are no other side effects associated with taking part in this study.
How to join a clinical trial
Prof Timothy Bishop
Cancer Research UK
NIHR Clinical Research Network: Cancer
University of Leeds