Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
A study looking at quality of life issues for people with cancer who are losing weight
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This study is looking at the
Some people with cancer have severe weight loss. You may hear this called cachexia (pronounced kak-ex-ee-a). Severe weight loss can affect many aspects of peoples’ lives.
Quality of life questionnaires that doctors already use ask some questions about weight loss. But in this study, researchers are developing and testing a questionnaire looking specifically at issues related to weight loss. They will use it alongside other questionnaires.
You are unlikely to get any direct benefit from taking part in this study. The information collected will help doctors and researchers to understand the quality of life issues that are most important for people with cancer who are losing weight.
Who can enter
You may be invited to join this trial if you have cancer and have been losing weight over the last few months.
This study will recruit people in a number of countries. It is in 3 parts.
If you join part 1, the researchers will interview you and ask about your experience of having cancer and losing weight. The interview will take about 20 minutes and the researchers will make an audio recording of it.
If you join part 2, the study team will ask you to look at a list of quality of life issues and rate the importance of each one, and whether it is relevant to you. They will also ask whether you think any important questions are missing. This should take about 20 minutes in total.
If you join part 3, the researchers will ask you a few questions about yourself, such as your employment history and your education. Then they will ask you to complete 2 questionnaires about your quality of life during the past week. One is a questionnaire that doctors already use and the other is the new questionnaire they are testing. They will ask for your views on the questionnaires and whether you think any important questions are missing. This should take about 35 minutes all together.
The researchers will ask everybody taking part for permission to look at their medical notes.
All the information you give is
In parts 1 and 2, you will have your interview either at one of your planned hospital appointments or at home. In part 3, all the interviews will take place at hospital.
You may find answering the questions distressing. If you do become distressed, you can stop the interview at any time. The researchers will give you contact details for the Clinical Nurse Specialist, who you may contact to discuss any issues.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Mr C.D. Johnson
European Organisation for Research and Treatment of Cancer (EORTC)
NIHR Clinical Research Network: Cancer
University Hospital Southampton NHS Foundation Trust