A study to develop a blood test for melanoma

Cancer type:

Skin cancer





This study is looking at developing a blood test that can detect melanoma at an early stage.

The aim of the study is to find out if a blood test can find melanoma cells circulating in the blood stream. This is a pilot study. If the test works, then researchers hope it will lead to a further study with more people.

Please note - you will not get any direct benefit from taking part in this study but it may help people in the future.

Who can enter

You can enter this trial if you

  • Have been diagnosed with melanoma that has spread
  • Are waiting to have surgery or treatment for your advanced melanoma at the University Hospitals of Leicester NHS Trust

You cannot enter this trial if you have a known infection in your blood stream.

Trial design

This trial will recruit 500 people in Leicester. If you agree to take part, you will be asked to give blood samples. These will be taken when you visit the hopsital as part of your usual care. 

Researchers will ask your permission to use tissue from your melanoma that was taken as part of your usual care.   

Hospital visits

There are no extra hospital visits involved with this study. You have the 2 blood tests during routine hospital visits.

Side effects

You may have some discomfort when the needle is put into your vein to take the blood sample. As with any blood test, there may be some mild bruising around the site, but this will clear after a week or two.



Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Dr G. Saldanha

Supported by

Experimental Cancer Medicine Centre (ECMC)
Hope against cancer
University Hospitals of Leicester NHS Trust
University of Leicester

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Charlie took part in a trial to try new treatments

A picture of Charlie

“I think it’s really important that people keep signing up to these type of trials to push research forward.”

Last reviewed:

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