Where this information about bisphosphonates comes from | Cancer Research UK
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Where this information about bisphosphonates comes from

Nurse and patients talking about cancer

This page tells you about the major sources of information that we use to put together this section.


About our information

All our information is checked by cancer specialists. The names of our specialist reviewers are at the end of this list. We also try to find patients to review all our sections. If you have had bisphosphonates, live in the UK, and would like to become a patient reviewer, you can write to us by clicking on the 'contact us' button on the right hand side of this page.



Electronic Medicines Compendium

British National Formulary

National Institute for Health and Care Excellence

  • Guideline on advanced breast cancer (Clinical guideline 81)
  • Guideline on prostate cancer (Clinical guideline 58)

Scottish Intercollegiate Guidelines Network

National Cancer Institute – USA

PubMed Central – National Institute of Health Medical Archive of Science Literature



Handbook of Cancer Chemotherapy (8th edition)
RT Skeel and SN Khleif 
Lippincott, Williams and Wilkins, 2011

Principles and practice of oncology (9th edition)
VT De Vita,  S Hellman and SA Rosenberg
Lippincott, Williams and Wilkins, 2011


UK and international guidelines

Bone health in cancer patients: European Society Medical Oncology Clinical Practice Guidelines. R. Coleman, J. J. Body, M. Aapro, P. Hadji and J. Herrstedt on behalf of the ESMO Guidelines Working Group. April 2014.


Reviews and articles

Future of bisphosphonates and denosumab for men with advanced prostate cancer. M Iranikhah, S Stricker, MK Freeman MK. Cancer Management and Research. 2014 May 3;6:217-224. 

Nonopioid Drugs in the Treatment of Cancer Pain. J Vardy, M Agar. Journal of Clinical Oncology. 2014 Jun 1;32(16):1677-1690. 

The Efficacy of Bisphosphonates in Preventing Aromatase Inhibitor Induced Bone Loss for Postmenopausal Women with Early Breast Cancer: A Systematic Review and Meta-Analysis. PP Anagha, S Sen. Journal of Oncology. 2014; 2014: 625060. 

The Role of Bisphosphonates in Medical Oncology and Their Association with Jaw Bone Necrosis. A Eid, J Atlas. Oral Maxillofacial Surgery Clinics of North America. 2014 May;26(2):231-237.

Bisphosphonates and other bone agents for breast cancer. (Cochrane review). MHF Wong, MR Stockler, N Pavlakis. Database of Systematic Reviews 2012, Issue 2. Art. No.: CD003474. DOI: 10.1002/14651858.CD003474.pub3.

Bisphosphonates in multiple myeloma. (Cochrane review). R Mhaskar, J Redzepovic, K Wheatley, OAC Clark, B Miladinovic, A Glasmacher, A Kumar, B Djulbegovic B. Database of Systematic Reviews 2012, Issue 5. 

Emerging role of bisphosphonates in the clinic – anti tumor activity and prevention of metastasis to bone. A Lipton. Cancer Treatment Review. 2008;34 Suppl 1:S25-30.

Zoledronic acid in the management of metastatic bone disease. TJ Polascik, V Mouraviev. Therapeutic Clinical Risk Managagement. 2008 Feb;4(1):261-8.


Specialist reviewers

Ms Debbie Wright

We would like to thank the pharmaceutical manufacturers who have answered our questions during the compilation of this information. 

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Updated: 5 June 2014