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Where this information about genes and inherited risk comes from

This page tells you about the major sources of information that we use to put together this section of our patient information.

 

About Cancer Research UK patient information

All our information is checked by cancer specialists. The names of our specialist reviewers are at the end of this list. 

We also try to find patients to review all our sections. If you have had cancer gene testing because you are thought to be at high risk (and live in the UK) you can help us by becoming a reviewer. Write to us by clicking on 'contact us'.

 

Websites

Cancer Research UK
CancerStats Series

UK Genetic testing network (UKGTN) Website (Accessed March 2015)
Has a database of the genetic tests available in the UK.

Clinical molecular genetics society (CMGS)
The CMGS is part of British Society for Human Genetics
Contains a list of the genetic laboratories.

Genetics home reference website (American) (accessed April 2015)

National Office of Statistics
The Health statistics section has information about the latest trends in the health of the UK
(Office for National Statistics, Health Statistics Quarterly Autumn 2000 p78)

 

Books

Cancer Biology (3rd edition) 
JB King and MW Robins
Pearson – Prentice Hall

Principles and practice of oncology (9th edition)
VT De Vita, S Hellman and SA Rosenberg
Lippincott, Williams and Wilkins, 2011

Cancer and its management (6th edition)
Tobias J and Hochhauser D
Blackwell Science, 2010

 

UK and international guidelines

National Institute for Health and Care Excellence guidelines (NICE)

Familial breast cancer: Classification and care of people at risk of familial breast cancer and management of breast cancer and related risks in people with a family history of breast cancer. Published June 2013.

Colonoscopic surveillance for prevention of colorectal cancer in people with ulcerative colitis, Crohn's disease or adenomas. Published March 2011.

Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002). Stuart R Cairns and others.Developed on behalf of The British Society of Gastroenterology, and the Association of Coloproctology for Great Britain and Ireland. Gut, 2010.

Guidance on gastrointestinal surveillance for hereditary non-polyposis colorectal cancer, familial adenomatous polypolis, juvenile polyposis, and Peutz-Jeghers syndrome.
MG Dunlop (British Society for Gastroenterology). Gut,
Volume 51 Supplement 5:V21-7. Oct 2002.

Guidance on large bowel surveillance for people with two first degree relatives with colorectal cancer or one first degree relative diagnosed with colorectal cancer under 45 years. MG Dunlop (British Society for Gastroenterology). Gut,
Volume 51 Supplement 5:V17-20. Oct 2002.

 

Articles and reviews

Familial risks for cancer as the basis for evidence-based clinical referral and Counselling.
K Hemminki et al. The Oncologist, Volume 13, pp239-247. March 2008.

Hereditary cancer predisposition syndromes. JE Garber and K Offit. Journal of Clinical Oncology, Volume 10;23 (2) pp 276-92 January 2005.

 

Specialist Reviewers

Ms. Tara Clancy (Consultant Genetic Counsellor/Honorary Senior Lecturer) 
Prof. Gareth Evans
Dr Paul Pharoah, PhD, FRCP (Consultant in public health medicine)

 

Diagrams

Dee McLean - MeDee Art, Medical Illustration

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Updated: 13 April 2015