Find out what teysuno is, how you have it and other important information about taking teysuno.
Teysuno (prounounced tay-sun-oh) is a chemotherapy drug made up of the following drugs:
- Tegafur – the body changes tegafur into a common chemotherapy drug called fluorouracil
- Gimeracil – which makes tegafur last longer in the body so you need a lower dose
- Oteracil – this protects normal cells and so reduces the side effects
It is a treatment for advanced stomach cancer. You have it in combination with another chemotherapy drug called cisplatin.
You may also teysuno as part of clinical trials for other cancers.
How it works
Teysuno is one of a group of chemotherapy drugs known as the anti metabolites. These stop cells making and repairing DNA. Cancer cells need to make and repair DNA in order to grow and multiply.
How you have it
Teysuno is a capsule. You take the capsules twice a day, morning and evening. Swallow them whole with plenty of water. You should take the capsules either an hour before eating or an hour after eating.
Taking your capsules
You should take the right dose, not more or less.
Never stop taking a cancer drug without talking to your specialist first.
When you have it
You usually take teysuno twice a day for 3 weeks and then don’t take it for a week. This is one cycle of treatment. Then your next cycle of treatment starts. You usually continue taking it in this way for as long as it works.
Tests during treatment
You have blood tests before starting treatment and during your treatment. They check your levels of blood cells and other substances in the blood. They also check how well your liver and kidneys are working.
Other medicines, foods and drink
Cancer drugs can interact with some other medicines and herbal products. Tell your doctor or pharmacist about any medicines you are taking. This includes vitamins, herbal supplements and over the counter remedies.
Pregnancy and contraception
This drug may harm a baby developing in the womb. It is important not to become pregnant or father a child while you are having treatment with this drug and for at least 6 months afterwards. Talk to your doctor or nurse about effective contraception before starting treatment.
We don’t know how this treatment might affect fertility. You may not be able to become pregnant or father a child after treatment with this drug. Talk to your doctor before starting treatment if you think you may want to have a baby in the future.
Some men might be able to store sperm before starting treatment. Some women might be able to store eggs or embryos before treatment.
Don’t breastfeed during this treatment because the drug may come through in your breast milk.
Treatment for other conditions
Always tell other doctors, nurses or dentists that you’re having this treatment if you need treatment for anything else, including teeth problems.
Don’t have immunisations with live vaccines while you’re having treatment and for at least 6 months afterwards.
In the UK, live vaccines include rubella, mumps, measles, BCG, yellow fever and Zostavax (shingles vaccine).
- have other vaccines, but they might not give you as much protection as usual
- have the flu vaccine
- be in contact with other people who've had live vaccines as injections
Avoid contact with people who’ve had live vaccines taken by mouth (oral vaccines). This includes the rotavirus vaccine given to babies. The virus is in the baby’s urine for up to 2 weeks and can make you ill. So, you mustn't change their nappies for 2 weeks after their vaccination.
You also need to avoid anyone who has had oral polio or typhoid vaccination recently.
More information about this treatment
For further information about this treatment go to the electronic Medicines Compendium (eMC) website.
You can report any side effect you have to the Medicines Health and Regulatory Authority (MHRA) as part of their Yellow Card Scheme.